Amoxicillin Sodium and Clavulanate Potassium 阿莫西林钠克拉维酸钾
OBJECTIVE To study the formulation, preparation and dissolution of amoxicillin and clavulanate potassium tablets.
目的：研究阿莫西林克拉维酸钾片处方及工艺，并考察其溶出度。
Objective: to establish a high performance liquid chromatography method for simultaneous determination of amoxicillin and clavulanate potassium in amoxicillin and clavulanate potassium granules.
目的：建立高效液相色谱法同时测定阿莫西林克拉维酸钾颗粒中阿莫西林和克拉维酸钾的含量。
METHODS The impurity profiling changes of amoxicillin plus potassium clavulanate were compared with both amoxicillin and potassium clavulanate alone by HPLC.
方法采用HPLC，比较阿莫西林和克拉维酸钾单独存在及复方后杂质谱的变化。
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